FLUNIXIN VABRIELA
Non steroid anti-inflammatory –
Analgesic
Formula
Flunixin meglumine 50 mg/ml -
Injectable solution
Antiinflammatory, with antipyretic
analgesic and antiinflammatory action indicated for the treatment
of inflammation and pain for diverse alterations of the skeletal
muscle system and for the refief of the visceral pain associated
with colics.
USE INDICATIONS
In equine, it is specially
indicated in the treatment of inflammation of the skeletal muscle
system, arthritis and colics. As coadjuvant therapy in the treament
of diarrhea in colts, shock stages, respiratory diseases, ophtalmic
and general surgeries (pre and post surgery).
Canine: disc alterations,
arthritis, acute gastric dilatation and as coadjuvant in diarrhea,
shock, ophtalmic inflammations, general and ophtalmic surgery.
Bovine: As adjuvant theraphy in
acute respiratory disease, acute mastitis by coliform with endotoxic
shock, fever, pain , inflammation and diarrhea in calves.
DOSAGE AND WAYS OF
ADMINISTRATION:
Injectable, by intramuscular or
endovenous tract.
EQUINE: 1 ml/45 kg (1,1 mg/kg)
once a day
In case of colics endovenous tract
is recommended though it may be redosed according to the veterinary
phisician advice.
In endotoxemia: 1ml each 200
kg/day (0,25 mg/kg/day)
Do administer once a day, no
more than 5 consecutive days.
CANINE: 0,1 ml/10 kg (0,5 mg/kg)
once a day EV during no more than 3 days.
In ophtalmic indications: 0,05
ml/10 kg (0,25 mg/kg/day) during no more than 5 days. In case it is
used for presurgical it may be administered endovenous 30 minutes
before surgery.
Acute gastric dilatation: 0,2
ml/10 kg (1 mg/kg) EV just only one dose.
Obstruction of the
gastrointestinal tract: 0,1 ml/10 kg (0,5 mg/kg) endovenous one or
twice a day upto 30 days.
Repeat once a day during a
maximum of 3 days.
BOVINE: 2 ml/45 kg/day (2,2
mg/kg/day) as an onset dose, then 1 ml/45 kg (1,1 mg/kg) once a day.
If it is necessary, repeat each
24 hours but no more than 3 days.
CONTRAINDICATIONS:
It is contraindicated in feline.
Do no administer to pregnant
females.
Do not administer to animals
hypersensitive to the main drug.
Endoarterial injection should be
avoided (since it produces ataxia, uncoordination, hyperventilation
and muscle weakness)
Do not administer to animals with
gastrointestinal ulcers.
It is contraindicated in animals
with hepatic, renal or cardiac impairment.
Safety during pregnancy has not
been evaluated, anyway it could be used as long as the benefits of
the therapy are greater than the risks involved.
It may interact with other drugs,
as other non steroid antiinflammatories do, thereby serum levels
may be affected and also their duration such as oral anticoagulants,
other antiinflammatory agents, sulfonamides.
CAUTIONS:
Endovenous administration should
be slowly done.
Do not swallow
In intramuscular injection it is
advisable to divide the dose in two points.
Administer only to saddle horses.
Do not exceed recommended dose.
RESTRICTIONS OF USE:
Do not slaughter animals for human consumption upto 7 days from last
treatment. Milk from the 5 days after treatment must be rejected.
In saddle horses, discontinue
treatment 8 days before the competition.
PRESENTATION:
Bottles containing 10 and 25 ml
STORAGE:
Keep between 4º and 30ºC
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